Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages

Macrophages are critical effectors of the early innate response to bacteria in tissues. Phagocytosis and killing of bacteria are interrelated functions essential for bacterial clearance but the rate‐limiting step when macrophages are challenged with large numbers of the major medical pathogen Staphy...

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Bibliografske podrobnosti
izdano v:Cell Microbiol
Main Authors: Jubrail, Jamil, Morris, Paul, Bewley, Martin A., Stoneham, Simon, Johnston, Simon A., Foster, Simon J., Peden, Andrew A., Read, Robert C., Marriott, Helen M., Dockrell, David H.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778410/
https://ncbi.nlm.nih.gov/pubmed/26248337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12485
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