N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells

BACKGROUND: N-Hydroxyphthalimide (NHPI), an important chemical raw material, was found to have potent and selective anti-proliferative effect on human breast carcinoma BT-20 cells, human colon adenocarcinoma LoVo and HT-29 cells during our screening for anticancer compounds. The purpose of this stud...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Wang, Min, Zhou, Ankun, An, Tao, Kong, Lingmei, Yu, Chunlei, Liu, Jianmei, Xia, Chengfeng, Zhou, Hongyu, Li, Yan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778274/
https://ncbi.nlm.nih.gov/pubmed/26940018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0315-1
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