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Downregulation of Pink1 influences mitochondrial fusion–fission machinery and sensitizes to neurotoxins in dopaminergic cells

It is now well established that mitochondria are organelles that, far from being static, are subject to a constant process of change. This process, which has been called mitochondrial dynamics, includes processes of both fusion and fission. Loss of Pink1 (PTEN-induced putative kinase 1) function is...

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Publicat a:Neurotoxicology
Autors principals: Rojas-Charry, Liliana, Cookson, Mark R., Niño, Andrea, Arboleda, Humberto, Arboleda, Gonzalo
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778252/
https://ncbi.nlm.nih.gov/pubmed/24792327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2014.04.007
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