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Monocytic myeloid-derived suppressor cells from females, but not males, alleviate CVB3-induced myocarditis by increasing regulatory and CD4(+)IL-10(+) T cells

Coxsackievirus group B type 3 (CVB3) is a common etiologic agent of viral myocarditis and often causes sexually dimorphic myocarditis with increased incidence and mortality in male. So far, the underlying mechanism for the high male prevalence is not well elucidated. In this study, we deciphered the...

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Pubblicato in:Sci Rep
Autori principali: Su, Nan, Yue, Yan, Xiong, Sidong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778123/
https://ncbi.nlm.nih.gov/pubmed/26939768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22658
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