An Unexpected Transient Breakdown of the Blood Brain Barrier Triggers Passage of Large Intravenously Administered Nanoparticles

The highly restrictive blood-brain barrier (BBB) plays a critically important role in maintaining brain homeostasis and is pivotal for proper neuronal function. The BBB is currently considered the main limiting factor restricting the passage of large (up to 200 nm) intravenously administered nanopar...

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Foilsithe in:Sci Rep
Main Authors: Smith, Nicole M., Gachulincova, Ivana, Ho, Diwei, Bailey, Charlotte, Bartlett, Carole A., Norret, Marck, Murphy, John, Buckley, Alysia, Rigby, Paul J., House, Michael J., St. Pierre, Timothy, Fitzgerald, Melinda, Iyer, K. Swaminathan, Dunlop, Sarah A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778073/
https://ncbi.nlm.nih.gov/pubmed/26940762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22595
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