Intra-epidemic evolutionary dynamics of a Dengue virus type 1 population reveal mutant spectra that correlate with disease transmission

Dengue virus (DENV) is currently the most prevalent mosquito-borne viral pathogen. DENVs naturally exist as highly heterogeneous populations. Even though the descriptions on DENV diversity are plentiful, only a few studies have narrated the dynamics of intra-epidemic virus diversity at a fine scale....

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Udgivet i:Sci Rep
Main Authors: Hapuarachchi, Hapuarachchige Chanditha, Koo, Carmen, Kek, Relus, Xu, Helen, Lai, Yee Ling, Liu, Lilac, Kok, Suet Yheng, Shi, Yuan, Chuen, Raphael Lee Tze, Lee, Kim-Sung, Maurer-Stroh, Sebastian, Ng, Lee Ching
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778070/
https://ncbi.nlm.nih.gov/pubmed/26940650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22592
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