Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis

Cystic fibrosis (CF) results in inflammation, malabsorption of fats and other nutrients, and obstruction in the gastrointestinal (GI) tract, yet the mechanisms linking these disease manifestations to microbiome composition remain largely unexplored. Here we used metagenomic analysis to systematicall...

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Vydáno v:Sci Rep
Hlavní autoři: Manor, Ohad, Levy, Roie, Pope, Christopher E., Hayden, Hillary S., Brittnacher, Mitchell J., Carr, Rogan, Radey, Matthew C., Hager, Kyle R., Heltshe, Sonya L., Ramsey, Bonnie W., Miller, Samuel I., Hoffman, Lucas R., Borenstein, Elhanan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778032/
https://ncbi.nlm.nih.gov/pubmed/26940651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22493
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