Metagenomic evidence for taxonomic dysbiosis and functional imbalance in the gastrointestinal tracts of children with cystic fibrosis

Cystic fibrosis (CF) results in inflammation, malabsorption of fats and other nutrients, and obstruction in the gastrointestinal (GI) tract, yet the mechanisms linking these disease manifestations to microbiome composition remain largely unexplored. Here we used metagenomic analysis to systematicall...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Manor, Ohad, Levy, Roie, Pope, Christopher E., Hayden, Hillary S., Brittnacher, Mitchell J., Carr, Rogan, Radey, Matthew C., Hager, Kyle R., Heltshe, Sonya L., Ramsey, Bonnie W., Miller, Samuel I., Hoffman, Lucas R., Borenstein, Elhanan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778032/
https://ncbi.nlm.nih.gov/pubmed/26940651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22493
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