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An Evaluation of Active Learning Causal Discovery Methods for Reverse-Engineering Local Causal Pathways of Gene Regulation

Reverse-engineering of causal pathways that implicate diseases and vital cellular functions is a fundamental problem in biomedicine. Discovery of the local causal pathway of a target variable (that consists of its direct causes and direct effects) is essential for effective intervention and can faci...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ma, Sisi, Kemmeren, Patrick, Aliferis, Constantin F., Statnikov, Alexander
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778024/
https://ncbi.nlm.nih.gov/pubmed/26939894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22558
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