New role and molecular mechanism of Gadd45a in hepatic fibrosis

AIM: To investigate the role of Gadd45a in hepatic fibrosis and the transforming growth factor (TGF)-β/Smad signaling pathway. METHODS: Wild-type male BALB/c mice were treated with CCl(4) to induce a model of chronic liver injury. Hepatic stellate cells (HSCs) were isolated from the liver of BALB/c m...

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Bibliografische gegevens
Gepubliceerd in:World J Gastroenterol
Hoofdauteurs: Hong, Liang, Sun, Qing-Feng, Xu, Ting-Yan, Wu, Yang-He, Zhang, Hui, Fu, Rong-Quan, Cai, Fu-Jing, Zhou, Qing-Qing, Zhou, Ke, Du, Qing-Wei, Zhang, Dong, Xu, Shuang, Ding, Ji-Guang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Baishideng Publishing Group Inc 2016
Onderwerpen:
Basic Study
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778000/
https://ncbi.nlm.nih.gov/pubmed/26973416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i9.2779
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