Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliC

Clostridium difficile is a Gram-positive bacillus and is the leading cause of toxin-mediated nosocomial diarrhea following antibiotic use. C. difficile flagella play a role in colonization, adherence, biofilm formation, and toxin production, which might contribute to the overall virulence of certain...

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Publicado en:Emerg Microbes Infect
Autores principales: Ghose, Chandrabali, Eugenis, Ioannis, Sun, Xingmin, Edwards, Adrianne N, McBride, Shonna M, Pride, David T, Kelly, Ciarán P, Ho, David D
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777929/
https://ncbi.nlm.nih.gov/pubmed/26839147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2016.8
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