Mechanism by which nuclear factor-kappa beta (NF-kB) regulates ovine fetal pulmonary vascular smooth muscle cell proliferation

Platelet activating factor (PAF) modulates ovine fetal pulmonary hemodynamic. PAF acts through its receptors (PAFR) in pulmonary vascular smooth muscle cells (PVSMC) to phosphorylate and induce nuclear translocation of NF-kB p65 leading to PVSMC proliferation. However, the interaction of NF-kB p65 a...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Ogbozor, Uchenna D., Opene, Michael, Renteria, Lissette S., McBride, Shaemion, Ibe, Basil O.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777924/
https://ncbi.nlm.nih.gov/pubmed/26966681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2015.05.003
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