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VAMP-associated Proteins (VAP) as Receptors That Couple Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Proteostasis with Lipid Homeostasis
Unesterified cholesterol accumulates in late endosomes in cells expressing the misfolded cystic fibrosis transmembrane conductance regulator (CFTR). CFTR misfolding in the endoplasmic reticulum (ER) or general activation of ER stress led to dynein-mediated clustering of cholesterol-loaded late endos...
Gorde:
Argitaratua izan da: | J Biol Chem |
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Egile Nagusiak: | , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Biochemistry and Molecular Biology
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777854/ https://ncbi.nlm.nih.gov/pubmed/26740627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.692749 |
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