Extracellular matrix mediators of metastatic cell colonization characterized using scaffold mimics of the pre-metastatic niche

Metastatic tumor cells colonize the pre-metastatic niche, which is a complex microenvironment consisting partially of extracellular matrix (ECM) proteins. We sought to identify and validate novel contributors to tumor cell colonization using ECM coated poly(ε-caprolactone) (PCL) scaffolds as mimics...

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Publicado en:Acta Biomater
Autores principales: Aguado, Brian A., Caffe, Jordan R., Nanavati, Dhaval, Rao, Shreyas S., Bushnell, Grace G., Azarin, Samira M., Shea, Lonnie D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777643/
https://ncbi.nlm.nih.gov/pubmed/26844426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.01.043
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