Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain

Rabies virus P-protein is expressed as five isoforms (P1-P5) which undergo nucleocytoplasmic trafficking important to roles in immune evasion. Although nuclear import of P3 is known to be mediated by an importin (IMP)-recognised nuclear localization sequence in the N-terminal region (N-NLS), the mec...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rowe, Caitlin L., Wagstaff, Kylie M., Oksayan, Sibil, Glover, Dominic J., Jans, David A., Moseley, Gregory W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777398/
https://ncbi.nlm.nih.gov/pubmed/26939125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150477
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