Phase I adaptive dose-finding study of neoadjuvant gemcitabine combined with radiation therapy for patients with high-risk extremity and trunk soft tissue sarcoma

BACKGROUND: We sought to determine the maximum tolerated dose (MTD) of gemcitabine given concurrently with preoperative, fixed-dose external-beam radiation therapy (EBRT) for patients with resectable, high-risk extremity and trunk soft tissue sarcomas (STS). METHODS: Gemcitabine was administered on...

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Publicado no:Cancer
Main Authors: Tseng, William W., Zhou, Shouhao, To, Christina A., Thall, Peter F., Lazar, Alexander J., Pollock, Raphael E., Lin, Patrick P., Cormier, Janice N., Lewis, Valerae O., Feig, Barry W., Hunt, Kelly K., Ballo, Matthew T., Patel, Shreyaskumar, Pisters, Peter W.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777348/
https://ncbi.nlm.nih.gov/pubmed/26177983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29544
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