Alpha1 catalytic subunit of AMPK modulates contractile function of cardiomyocytes through phosphorylation of troponin I

AIMS: The specific role of AMPKα1 or AMPKα2 in mediating cardiomyocyte contractile function remains elusive. The present study investigated how AMPK activation modulates the contractility of isolated cardiomyocytes. MAIN METHODS: Mechanical properties and intracellular Ca(2+) properties were measure...

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Bibliografiske detaljer
Udgivet i:Life Sci
Main Authors: Chen, Si, Zhu, Ping, Guo, Hui-Ming, Solis, Raquel Sancho, Wang, Yanqing, Ma, Yina, Wang, Jinli, Gao, Junjie, Chen, Ji-Mei, Ge, Ying, Zhuang, Jian, Li, Ji
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777330/
https://ncbi.nlm.nih.gov/pubmed/24447627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2014.01.006
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