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Screening for Expressed Nonribosomal Peptide Synthetases and Polyketide Synthases Using LC-MS/MS-Based Proteomics

Liquid chromatography–mass spectrometry (LC-MS)-based proteomics is a powerful technique for the profiling of protein expression in cells in a high-throughput fashion. Herein we report a protocol using LC-MS/MS-based proteomics for the screening of enzymes involved in natural product biosynthesis, s...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Chen, Yunqiu, McClure, Ryan A., Kelleher, Neil L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777305/
https://ncbi.nlm.nih.gov/pubmed/26831706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3375-4_9
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