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Pharmacological comparison of a nonhuman primate and a rat model of oxaliplatin‐induced neuropathic cold hypersensitivity

Oxaliplatin is a first‐line treatment for colorectal cancer. However, shortly following treatment, cold‐evoked hypersensitivity appears in the extremities and over time, the pain is such that oxaliplatin dosing may need to be markedly reduced or even terminated. There is currently a lack of efficaci...

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Bibliografske podrobnosti
izdano v:Pharmacol Res Perspect
Main Authors: Shidahara, Yuka, Ogawa, Shinya, Nakamura, Mari, Nemoto, Shingo, Awaga, Yuji, Takashima, Miyuki, Hama, Aldric, Matsuda, Akihisa, Takamatsu, Hiroyuki
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777264/
https://ncbi.nlm.nih.gov/pubmed/26977304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.216
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