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Pharmacological comparison of a nonhuman primate and a rat model of oxaliplatin‐induced neuropathic cold hypersensitivity

Oxaliplatin is a first‐line treatment for colorectal cancer. However, shortly following treatment, cold‐evoked hypersensitivity appears in the extremities and over time, the pain is such that oxaliplatin dosing may need to be markedly reduced or even terminated. There is currently a lack of efficaci...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Shidahara, Yuka, Ogawa, Shinya, Nakamura, Mari, Nemoto, Shingo, Awaga, Yuji, Takashima, Miyuki, Hama, Aldric, Matsuda, Akihisa, Takamatsu, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777264/
https://ncbi.nlm.nih.gov/pubmed/26977304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.216
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