Claudin‐4 binder C‐CPE 194 enhances effects of anticancer agents on pancreatic cancer cell lines via a MAPK pathway

The C‐terminal fragment of Clostridium perfringens enterotoxin (C‐CPE) modulates the tight junction protein claudin and disrupts the tight junctional barrier. It also can enhance the effectiveness of anticancer agents. However, the detailed mechanisms of the effects of C‐CPE remain unclear in both n...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Kono, Tsuyoshi, Kondoh, Masuo, Kyuno, Daisuke, Ito, Tatsuya, Kimura, Yasutoshi, Imamura, Masafumi, Kohno, Takayuki, Konno, Takumi, Furuhata, Tomohisa, Sawada, Norimasa, Hirata, Koichi, Kojima, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777248/
https://ncbi.nlm.nih.gov/pubmed/27022469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.196
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