Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans

Inappropriate activation of innate immune responses in intestinal epithelial cells underlies the pathophysiology of inflammatory disorders of the intestine. Here we examine the physiological effects of immune hyperactivation in the intestine of the nematode Caenorhabditis elegans. We previously iden...

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Publicat a:G3 (Bethesda)
Autors principals: Cheesman, Hilary K., Feinbaum, Rhonda L., Thekkiniath, Jose, Dowen, Robert H., Conery, Annie L., Pukkila-Worley, Read
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2016
Matèries:
Genetics of Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777117/
https://ncbi.nlm.nih.gov/pubmed/26818074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.025650
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