PTPRG inhibition By DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia

While the cytogenetic and genetic characteristics of childhood acute lymphoblastic leukemias (ALL) are well studied, less clearly understood are the contributing epigenetic mechanisms that influence the leukemia phenotype. Our previous studies and others identified gene mutation (RAS) and DNA methyl...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Xiao, Jianqiao, Lee, Seung-Tae, Xiao, Yuanyuan, Ma, Xiaomei, Houseman, E. Andres, Hsu, Ling-I, Roy, Ritu, Wrensch, Margaret, de Smith, Adam J., Chokkalingam, Anand, Buffler, Patricia, Wiencke, John K., Wiemels, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776754/
https://ncbi.nlm.nih.gov/pubmed/24496747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28759
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