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Evolutionary Transition of Promoter and Gene Body DNA Methylation across Invertebrate–Vertebrate Boundary

Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is mostly targeted to a subset of transcription units (gene bodies). In a drastic contrast, vertebrate genomes are generally globall...

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Pubblicato in:Mol Biol Evol
Autori principali: Keller, Thomas E., Han, Priscilla, Yi, Soojin V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776710/
https://ncbi.nlm.nih.gov/pubmed/26715626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv345
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