Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Sarcopenia, or skeletal muscle atrophy, is a debilitating comorbidity of many physiological and pathophysiological processes, including normal aging. There are no approved therapies for sarcopenia, but the antihypertrophic myokine myostatin is a potential therapeutic target. Here, we show that treat...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Camporez, João-Paulo G., Petersen, Max C., Abudukadier, Abulizi, Moreira, Gabriela V., Jurczak, Michael J., Friedman, Glenn, Haqq, Christopher M., Petersen, Kitt Falk, Shulman, Gerald I.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776508/
https://ncbi.nlm.nih.gov/pubmed/26858428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525795113
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