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Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases.

Transforming growth factor beta 1 (TGF-beta 1) is a potent growth-inhibitory polypeptide. The mechanism of TGF-beta 1 inhibition has been related to its ability to prevent the hyperphosphorylation of retinoblastoma protein (pRb). Several lines of evidence have suggested that cell cycle-regulated pro...

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Main Authors: Geng, Y, Weinberg, R A
格式: Artigo
語言:Inglês
出版: 1993
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC47765/
https://ncbi.nlm.nih.gov/pubmed/7694291
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