TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells

Human urine cells (HUCs) can be reprogrammed into neural progenitor cells (NPCs) or induced pluripotent stem cells (iPSCs) with defined factors and a small molecule cocktail, but the underlying fate choice remains unresolved. Here, through sequential removal of individual compound from small molecul...

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Publicado no:Sci Rep
Main Authors: Wang, Lihui, Li, Xirui, Huang, Wenhao, Zhou, Tiancheng, Wang, Haitao, Lin, Aiping, Hutchins, Andrew Paul, Su, Zhenghui, Chen, Qianyu, Pei, Duanqing, Pan, Guangjin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776143/
https://ncbi.nlm.nih.gov/pubmed/26935433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22484
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