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CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients

OBJECTIVE: To assess if the percentage of CD3(+)CD4(+)CD62L(+) cells in cryopreserved peripheral blood mononuclear cells (PBMCs) (here termed %CD62L) can predict risk of developing progressive multifocal leukoencephalopathy (PML) and better inform the physician for benefit–risk assessment of nataliz...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Lieberman, Linda A., Zeng, Wanyong, Singh, Carol, Wang, Wenting, Otipoby, Kevin L., Loh, Christine, Plavina, Tatiana, Gorelik, Leonid, Ransohoff, Richard M., Cahir-McFarland, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776091/
https://ncbi.nlm.nih.gov/pubmed/26718566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002314
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