In Vitro Activity of Gepotidacin, a Novel Triazaacenaphthylene Bacterial Topoisomerase Inhibitor, against a Broad Spectrum of Bacterial Pathogens

Gepotidacin inhibits bacterial DNA replication through a mode different from that of fluoroquinolones. Gepotidacin and comparators were tested by broth and agar dilution against clinical isolates. The in vitro activities of gepotidacin were comparable against methicillin-susceptible and -resistant S...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Biedenbach, D. J., Bouchillon, S. K., Hackel, M., Miller, L. A., Scangarella-Oman, N. E., Jakielaszek, C., Sahm, D. F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776004/
https://ncbi.nlm.nih.gov/pubmed/26729499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02820-15
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