Mutation in the Hepatitis E Virus Polymerase and Outcome of Ribavirin Therapy

Hepatitis E virus (HEV) can lead to chronic infection in solid-organ transplant patients. Ribavirin is efficient for treatment of chronically infected patients. Recently, the1634R mutation in the HEV polymerase has been associated with treatment failure. However, it is unclear if this mutation can b...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lhomme, Sebastien, Kamar, Nassim, Nicot, Florence, Ducos, Jacques, Bismuth, Michael, Garrigue, Valerie, Petitjean-Lecherbonnier, Joelle, Ollivier, Isabelle, Alessandri-Gradt, Elodie, Goria, Odile, Barth, Heidi, Perrin, Peggy, Saune, Karine, Dubois, Martine, Carcenac, Romain, Lefebvre, Caroline, Jeanne, Nicolas, Abravanel, Florence, Izopet, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775994/
https://ncbi.nlm.nih.gov/pubmed/26711757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02496-15
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