The Staphylococcus aureus Chaperone PrsA Is a New Auxiliary Factor of Oxacillin Resistance Affecting Penicillin-Binding Protein 2A

Expression of the methicillin-resistant S. aureus (MRSA) phenotype results from the expression of the extra penicillin-binding protein 2A (PBP2A), which is encoded by mecA and acquired horizontally on part of the SCCmec cassette. PBP2A can catalyze dd-transpeptidation of peptidoglycan (PG) because o...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Jousselin, Ambre, Manzano, Caroline, Biette, Alexandra, Reed, Patricia, Pinho, Mariana G., Rosato, Adriana E., Kelley, William L., Renzoni, Adriana
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775990/
https://ncbi.nlm.nih.gov/pubmed/26711778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02333-15
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