β-Lactamase Characterization of Gram-Negative Pathogens Recovered from Patients Enrolled in the Phase 2 Trials for Ceftazidime-Avibactam: Clinical Efficacies Analyzed against Subsets of Molecularly Characterized Isolates

The correlation of the clinical efficacies of ceftazidime-avibactam and comparators (carbapenems) was evaluated against baseline Gram-negative isolates having characterized β-lactam resistance mechanisms from complicated urinary tract infection (cUTI) and complicated intra-abdominal infection (cIAI)...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Mendes, Rodrigo E., Castanheira, Mariana, Gasink, Leanne, Stone, Gregory G., Nichols, Wright W., Flamm, Robert K., Jones, Ronald N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775982/
https://ncbi.nlm.nih.gov/pubmed/26666936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01173-15
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