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Stearylamine Liposomal Delivery of Monensin in Combination with Free Artemisinin Eliminates Blood Stages of Plasmodium falciparum in Culture and P. berghei Infection in Murine Malaria

The global emergence of drug resistance in malaria is impeding the therapeutic efficacy of existing antimalarial drugs. Therefore, there is a critical need to develop an efficient drug delivery system to circumvent drug resistance. The anticoccidial drug monensin, a carboxylic ionophore, has been sh...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rajendran, Vinoth, Rohra, Shilpa, Raza, Mohsin, Hasan, Gulam Mustafa, Dutt, Suparna, Ghosh, Prahlad C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775978/
https://ncbi.nlm.nih.gov/pubmed/26666937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01796-15
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