Emergence of cfr-Mediated Linezolid Resistance in a Methicillin-Resistant Staphylococcus aureus Epidemic Clone Isolated from Patients with Cystic Fibrosis

Resistance to linezolid (LZD) in methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients with cystic fibrosis (CF) is due mainly to ribosomal mutations. We report on four CF patients with LZD-resistant MRSA bronchopulmonary infections by strains carrying the cfr gene. Strains from...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: de Dios Caballero, Juan, Pastor, María Dolores, Vindel, Ana, Máiz, Luis, Yagüe, Genoveva, Salvador, Carme, Cobo, Marta, Morosini, María-Isabel, del Campo, Rosa, Cantón, Rafael
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775957/
https://ncbi.nlm.nih.gov/pubmed/26666940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02067-15
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