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ESR1 Mutations in Breast Cancer: Proof of Concept Challenges Clinical Action

Wang and colleagues demonstrate that digital droplet PCR (ddPCR) identified ESR1 mutations in 7% of primary breast cancers. ESR1 mutations were also readily detected in metastatic tissues and circulating tumor DNA in the blood. These results suggest that ddPCR may be amendable for monitoring tumor b...

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Bibliografische gegevens
Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Gu, Guowei, Fuqua, Suzanne A.W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775407/
https://ncbi.nlm.nih.gov/pubmed/26700205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2549
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