FSensitive detection of mono- and polyclonal ESR1 mutations in primary tumors, metastatic lesions and cell free DNA of breast cancer patients

PURPOSE: Given the clinical relevance of ESR1 mutations as potential drivers of resistance to endocrine therapy, this study used sensitive detection methods to determine the frequency of ESR1 mutations in primary and metastatic breast cancer, and in cell free DNA (cfDNA). PATIENTS AND METHODS: Six E...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Wang, Peilu, Bahreini, Amir, Gyanchandani, Rekha, Lucas, Peter C., Hartmaier, Ryan J., Watters, Rebecca J., Jonnalagadda, Amruth R., Trejo Bittar, Humberto E., Berg, Aaron, Hamilton, Ronald L., Kurland, Brenda F., Weiss, Kurt R., Mathew, Aju, Leone, Jose Pablo, Davidson, Nancy E, Nikiforova, Marina N., Brufsky, Adam M., Ambros, Tadeu F., Stern, Andrew M., Puhalla, Shannon L., Lee, Adrian V., Oesterreich, Steffi
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775406/
https://ncbi.nlm.nih.gov/pubmed/26500237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1534
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki