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Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1

The heat shock response is a universal homeostatic cell autonomous reaction of organisms to cope with adverse environmental conditions. In mammalian cells, this response is mediated by the heat shock transcription factor Hsf1, which is monomeric in unstressed cells and upon activation trimerizes, an...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Hentze, Nikolai, Le Breton, Laura, Wiesner, Jan, Kempf, Georg, Mayer, Matthias P
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775227/
https://ncbi.nlm.nih.gov/pubmed/26785146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11576
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