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The p38 MAP kinase pathway modulates the hypoxia response and glutamate receptor trafficking in aging neurons
Neurons are sensitive to low oxygen (hypoxia) and employ a conserved pathway to combat its effects. Here, we show that p38 MAP Kinase (MAPK) modulates this hypoxia response pathway in C. elegans. Mutants lacking p38 MAPK components pmk-1 or sek-1 resemble mutants lacking the hypoxia response compone...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775213/ https://ncbi.nlm.nih.gov/pubmed/26731517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12010 |
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