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Neuronal Orphan G-Protein Coupled Receptor Proteins Mediate Plasmalogens-Induced Activation of ERK and Akt Signaling

The special glycerophospholipids plasmalogens (Pls) are enriched in the brain and reported to prevent neuronal cell death by enhancing phosphorylation of Akt and ERK signaling in neuronal cells. Though the activation of Akt and ERK was found to be necessary for the neuronal cells survival, it was no...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Hossain, Md. Shamim, Mineno, Kurumi, Katafuchi, Toshihiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775022/
https://ncbi.nlm.nih.gov/pubmed/26934370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150846
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