Hyaluronic Acid Suppresses the Expression of Metalloproteinases in Osteoarthritic Cartilage Stimulated Simultaneously by Interleukin 1β and Mechanical Load

PURPOSE: In patients with osteoarthritis (OA), intraarticular injection of hyaluronic acid (HA) frequently results in reduced pain and improved function for prolonged periods of time, i.e. more than 6 months. However, the mechanisms underlying these effects are not fully understood. Our underlying h...

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Veröffentlicht in:PLoS One
Hauptverfasser: Pohlig, Florian, Guell, Florian, Lenze, Ulrich, Lenze, Florian W., Mühlhofer, Heinrich M. L., Schauwecker, Johannes, Toepfer, Andreas, Mayer-Kuckuk, Philipp, von Eisenhart-Rothe, Rüdiger, Burgkart, Rainer, Salzmann, Gian M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774918/
https://ncbi.nlm.nih.gov/pubmed/26934732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150020
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