Protease inhibitors targeting coronavirus and filovirus entry

In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases. The respective enzymes are thus excellent targets for antiviral intervention. In cell culture, a...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Zhou, Yanchen, Vedantham, Punitha, Lu, Kai, Agudelo, Juliet, Carrion, Ricardo, Nunneley, Jerritt W., Barnard, Dale, Pöhlmann, Stefan, McKerrow, James H., Renslo, Adam R., Simmons, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774534/
https://ncbi.nlm.nih.gov/pubmed/25666761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2015.01.011
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