Structural and Functional Characterization of a Single-Chain Form of the Recognition Domain of Complement Protein C1q

Complement C1q is a soluble pattern recognition molecule comprising six heterotrimeric subunits assembled from three polypeptide chains (A–C). Each heterotrimer forms a collagen-like stem prolonged by a globular recognition domain. These recognition domains sense a wide variety of ligands, including...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Moreau, Christophe, Bally, Isabelle, Chouquet, Anne, Bottazzi, Barbara, Ghebrehiwet, Berhane, Gaboriaud, Christine, Thielens, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774423/
https://ncbi.nlm.nih.gov/pubmed/26973654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00079
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