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Inhibition of mTOR promotes hyperthermia sensitivity in SMMC-7721 human hepatocellular carcinoma cell line

The mammalian target of rapamycin (mTOR) is a critical mediator of the phosphoinositide 3-kinase/protein kinase B/mTOR signaling pathway, and mTOR activity is induced following heat shock. Thermotherapy is used to treat hepatocellular carcinoma (HCC). However, the role of mTOR in modulating thermose...

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Publicado en:Exp Ther Med
Autores principales: WANG, QING-LIANG, LIU, BO, LI, XIAO-JIE, HU, KUN-PENG, ZHAO, KUN, YE, XIAO-MING
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774347/
https://ncbi.nlm.nih.gov/pubmed/26998020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.2979
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