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Murine mesothelin: characterization, expression, and inhibition of tumor growth in a murine model of pancreatic cancer

BACKGROUND: Mesothelin has attracted much interest as a tumor specific antigen; it has been reported to promote tumor development and to be a good target for cancer treatment. Most studies to date have used human mesothelin in immunocompromised mice. Since these models do not allow for study of the...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zervos, Emmanuel, Agle, Steven, Freistaedter, Andrew G., Jones, Gwendolyn J. B., Roper, Rachel L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774190/
https://ncbi.nlm.nih.gov/pubmed/26931187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0314-2
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