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Anti-TNF certolizumab pegol induces antioxidant response in human monocytes via reverse signaling

BACKGROUND: Anti TNF drugs have been widely used in rheumatoid arthritis (RA) but only 70 to 80 % of patients respond to this therapy. Exploring the mode of action of anti-TNF drugs remains important in order to improve the efficiency of the treatment and enhance our knowledge of inflammation. TNF-α...

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Publicado en:Arthritis Res Ther
Autores principales: Boyer, Jean Frédéric, Baron, Michel, Constantin, Arnaud, Degboé, Yannick, Cantagrel, Alain, Davignon, Jean-Luc
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774095/
https://ncbi.nlm.nih.gov/pubmed/26932562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0955-8
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