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Activation of intracellular calcium signaling in osteoblasts colocalizes with the formation of post-yield diffuse microdamage in bone matrix

Previous studies demonstrated that extracellular calcium efflux ([Ca(2+)](E)) originates from the regions of bone extracellular matrix that are undergoing microdamage. Such [Ca(2+)](E) is reported to induce the activation of intracellular calcium signaling ([Ca(2+)](I)) in MC3T3-E1 cells. The curren...

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Detalhes bibliográficos
Publicado no:Bonekey Rep
Main Authors: Jung, Hyungjin, Akkus, Ozan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774084/
https://ncbi.nlm.nih.gov/pubmed/26962448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2016.5
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