Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.

Lignende værker

• Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10
  Udgivet: (1996)
• Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.
  af: Gazzinelli, R T, et al.
  Udgivet: (1993)
• Priming for high interferon-gamma production induced by interleukin-12 in both CD4+ and CD8+ T cell clones from HIV-infected patients.
  af: Paganin, C, et al.
  Udgivet: (1995)
• The interleukin 12 p40 gene promoter is primed by interferon gamma in monocytic cells
  Udgivet: (1996)
• Role of Interleukin-4 (IL-4), IL-12, and Gamma Interferon in Primary and Vaccine-Primed Immune Responses to Friend Retrovirus Infection
  af: Dittmer, Ulf, et al.
  Udgivet: (2001)