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MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3

Steroid-induced osteonecrosis of femoral head (ONFH) is a serious complication of glucocorticoid (GC) use. We investigated the differential expression of miRs in the mesenchymal stem cells (MSCs) of patients with ONFH, and aimed to explain the relationship between GC use and the development of MSC d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hao, Cheng, Yang, Shuhua, Xu, Weihua, Shen, Jacson K., Ye, Shunan, Liu, Xianzhe, Dong, Zhe, Xiao, Baojun, Feng, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773864/
https://ncbi.nlm.nih.gov/pubmed/26932538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22599
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