Silencing MicroRNA-155 Attenuates Cardiac Injury and Dysfunction in Viral Myocarditis via Promotion of M2 Phenotype Polarization of Macrophages

Macrophage infiltration is a hallmark feature of viral myocarditis. As studies have shown that microRNA-155 regulates the differentiation of macrophages, we aimed to investigate the role of microRNA-155 in VM. We report that silencing microRNA-155 protects mice from coxsackievirus B3 induced myocard...

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Vydáno v:Sci Rep
Hlavní autoři: Zhang, Yingying, Zhang, Mengying, Li, Xueqin, Tang, Zongsheng, Wang, Xiangmin, Zhong, Min, Suo, Qifeng, Zhang, Yao, Lv, Kun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773853/
https://ncbi.nlm.nih.gov/pubmed/26931072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22613
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