Smac127 Has Proapoptotic and Anti-Inflammatory Effects on Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Rheumatoid arthritis (RA) is characterized by synovial inflammation and hyperplasia. Fibroblast-like synoviocytes (FLSs) are apoptosis-resistant and contribute to the pathogenesis of RA by producing cytokines and proteolytic enzymes, which degrade the extracellular matrix. We evaluated the proapopto...

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Publicat a:Mediators Inflamm
Autors principals: Lattuada, D., Gualtierotti, R., Crotta, K., Seneci, P., Ingegnoli, F., Corradini, C., Viganò, R., Marelli, O., Casnici, C.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773553/
https://ncbi.nlm.nih.gov/pubmed/26989333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6905678
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