Peptide-Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic-Modified Polyethylenimine

Polyethylenimine (PEI) is considered to be a promising non-viral gene delivery vector. To solve the toxicity versus efficacy and tumor-targeting challenges of PEI used as gene delivery vector, we constructed a novel non-viral vector DR5-TAT-modified Pluronic-PEI (Pluronic-PEI-DR5-TAT), which was bas...

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Veröffentlicht in:Nanoscale Res Lett
Hauptverfasser: Wu, Zhaoyong, Zhan, Shuyu, Fan, Wei, Ding, Xueying, Wu, Xin, Zhang, Wei, Fu, Yinghua, Huang, Yueyan, Huang, Xuan, Chen, Rubing, Li, Mingjuan, Xu, Ningyin, Zheng, Yongxia, Ding, Baoyue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
Schlagworte:
Nano Express
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773318/
https://ncbi.nlm.nih.gov/pubmed/26932761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11671-016-1337-5
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